NVP-BGT226
- Product Name
- NVP-BGT226
- CAS No.
- 1245537-68-1
- Chemical Name
- NVP-BGT226
- Synonyms
- CS-382;BGT226;NVP-BGT226;BGT-226 maleate;BGT226 (NVP-BGT226);NVP-BGT226 (BGT226);NVP-BGT226 (maleate);NVP-BGT226 USP/EP/BP;NVP-BGT226 (free base);BGT-226;NVP BGT226 (BGT226)
- CBNumber
- CB52589704
- Molecular Formula
- C28H25F3N6O2.C4H4O4
- Formula Weight
- 650.6044696
- MOL File
- 1245537-68-1.mol
NVP-BGT226 Property
- Melting point:
- >215°C (dec.)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly)
- form
- Solid
- color
- White to Pale Yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 22142
- Product name
- NVP-BGT226
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $40
- Updated
- 2024/03/01
- Product number
- 22142
- Product name
- NVP-BGT226
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $146
- Updated
- 2024/03/01
- Product number
- 22142
- Product name
- NVP-BGT226
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $274
- Updated
- 2024/03/01
- Product number
- 22142
- Product name
- NVP-BGT226
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $632
- Updated
- 2024/03/01
- Product number
- B367500
- Product name
- BGT226
- Packaging
- 5mg
- Price
- $250
- Updated
- 2021/12/16
NVP-BGT226 Chemical Properties,Usage,Production
Uses
BGT 226 is a novel phosphatidyl inositol-3 kinase/mammalian target of rapamycin (PI3K/mTOR ) dual inhibitor which has shown to be effective with gefitinib in epidermal growth factor receptor (EGFR) inhibitor-sensitive non-small cell lung cancer (NSCLC) therapy.
Definition
ChEBI: BGT226 is the maleate salt of 8-(6-methoxypyridin-3-yl)-3-methyl-1-[4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl]-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one. A dual PI3K/mTOR inhibitor. It has a role as an antineoplastic agent, a mTOR inhibitor and an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor. It contains a BGT226(1+).
target
PI3Kα
NVP-BGT226 Preparation Products And Raw materials
Raw materials
Preparation Products
NVP-BGT226 Suppliers
- Tel
- 44-20819178-90 02081917890
- Fax
- (0)2080432064
- info@novachemistry.com
- Country
- United Kingdom
- ProdList
- 4381
- Advantage
- 58
View Lastest Price from NVP-BGT226 manufacturers
- Product
- 1-(3-(Trifluoromethyl)-4-(piperazin-1-yl)phenyl)-8-(6-methoxypyridin-3-yl)-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one maleic acid salt 1245537-68-1
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200KG
- Release date
- 2019-07-01